Front and back by Rho and Rac

被引：42

作者：

Burridge, Keith ^{[1
]}

Doughman, Renee ^{[1
]}

机构：

[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

来源：

NATURE CELL BIOLOGY | 2006年 / 8卷 / 08期

关键词：

D O I：

10.1038/ncb0806-781

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The RhoGTPases Rac and Rho are important for orchestrating cytoskeletal dynamics during cell migration and crosstalk to antagonize each others' activities. The discovery of a Rac GTPase activating protein ( GAP) that is regulated by Rho and Rho kinase ( ROCK) provides a new basis for this crosstalk.

引用

页码：781 / 782

页数：2

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