Superparamagnetic iron oxide as an efficient catalyst for the one-pot, solvent-free synthesis of α-aminonitriles

被引：109

作者：

Mojtahedi, Mohammad M. ^{[1
]}

Abaee, M. Saeed ^{[1
]}

Alishiri, Tooba ^{[1
]}

机构：

[1] Chem & Chem Engn Res Ctr Iran, Tehran, Iran

来源：

TETRAHEDRON LETTERS | 2009年 / 50卷 / 20期

关键词：

STRECKER REACTION; MAGNETIC NANOPARTICLES; HETEROGENEOUS CATALYST; REUSABLE CATALYST; OXIDATION; PROTECTION; PALLADIUM; ALDEHYDES; CHLORIDE; AMINES;

D O I：

10.1016/j.tetlet.2009.02.199

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Superparamagnetic Fe3O4 is shown to act as a very efficient catalyst for the one-pot, three-component synthesis of alpha-aminonitriles from aldehydes, amines, and TMSCN. The catalyst is easily recovered by the use of an external magnet and reused in several reactions without any noticeable loss of activity. The products are obtained rapidly at room temperature in good purity upon separation of the catalyst and evaporation of the volatiles of the reaction mixture. (C) 2009 Elsevier Ltd. All rights reserved.

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页码：2322 / 2325

页数：4

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