Gene dosage and linezolid resistance in Enterococcus faecium and Enterococcus faecalis

被引：202

作者：

Marshall, SH

Donskey, CJ

Hutton-Thomas, R

Salata, RA

Rice, LB

机构：

[1] Dept Vet Affairs Med Ctr, Res & Med Serv, Cleveland, OH USA

[2] Case Western Reserve Univ, Sch Med, Div Infect Dis, Cleveland, OH USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 10期

关键词：

D O I：

10.1128/AAC.46.10.3334-3336.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Resistance to linezolid has been associated with a G2576U mutation in domain V of the 23S rRNA. We analyzed nine clinical isolates of linezolid-resistant enterococci and showed a clear association between the number of 23S rRNA genes containing this mutation and the level of linezolid resistance expressed.

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页码：3334 / 3336

页数：3

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