学术探索
学术期刊
新闻热点
数据分析
智能评审

Analytical aspects of mass spectrometry and proteomics

被引：38
作者：
Mo, WJ
Karger, BL
机构：
[1] Northeastern Univ, Barnett Inst, Boston, MA 02115 USA
[2] Northeastern Univ, Dept Chem, Boston, MA 02115 USA
来源：
CURRENT OPINION IN CHEMICAL BIOLOGY | 2002年 / 6卷 / 05期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S1367-5931(02)00379-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Mass spectrometry plays an essential role in proteomics analysis and research. In recent years, it has been increasingly recognized that a key to proteomics using mass spectrometry relies not only on the instrument itself, but also on the analytical strategies and front-end sample-handling techniques. The advances of separations and mass spectrometry are having an increasing impact on the discovery of disease biomarkers and the understanding of cellular processes.
引用
收藏
页码：666 / 675
页数：10
相关论文
共 123 条
  • [1] The cell as a collection of protein machines: Preparing the next generation of molecular biologists
    Alberts, B
    [J]. CELL, 1998, 92 (03) : 291 - 294
  • [2] Axin-mediated CKI phosphorylation of β-catenin at Ser 45:: a molecular switch for the Wnt pathway
    Amit, S
    Hatzubai, A
    Birman, Y
    Andersen, JS
    Ben-Shushan, E
    Mann, M
    Ben-Neriah, Y
    Alkalay, I
    [J]. GENES & DEVELOPMENT, 2002, 16 (09) : 1066 - 1076
  • [3] ISOLATION OF PHOSPHOPROTEINS BY IMMOBILIZED METAL (FE-3+) AFFINITY-CHROMATOGRAPHY
    ANDERSSON, L
    PORATH, J
    [J]. ANALYTICAL BIOCHEMISTRY, 1986, 154 (01) : 250 - 254
  • [4] Matrix assisted laser desorption/ionization coupled with quadrupole/orthogonal acceleration time-of-flight mass spectrometry for protein discovery, identification, and structural analysis
    Baldwin, MA
    Medzihradszky, KF
    Lock, CM
    Fisher, B
    Settineri, TA
    Burlingame, AL
    [J]. ANALYTICAL CHEMISTRY, 2001, 73 (08) : 1707 - 1720
  • [5] Resolving isomeric peptide mixtures: A combined HPLC/ion mobility-TOFMS analysis of a 4000-component combinatorial library
    Barnes, CAS
    Hilderbrand, AE
    Valentine, SJ
    Clemmer, DE
    [J]. ANALYTICAL CHEMISTRY, 2002, 74 (01) : 26 - 36
  • [6] Dynamic range expansion applied to mass spectrometry based on data-dependent selective ion ejection in capillary liquid chromatography Fourier transform ion cyclotron resonance for enhanced proteome characterization
    Belov, ME
    Anderson, GA
    Angell, NH
    Shen, YF
    Tolic, N
    Udseth, HR
    Smith, RD
    [J]. ANALYTICAL CHEMISTRY, 2001, 73 (21) : 5052 - 5060
  • [7] A new technique for unbiased external ion accumulation in a quadrupole two-dimensional ion trap for electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry
    Belov, ME
    Nikolaev, EN
    Alving, K
    Smith, RD
    [J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2001, 15 (14) : 1172 - 1180
  • [8] Controlled ion fragmentation in a 2-D quadrupole ion trap for external ion accumulation in ESI FTICR mass spectrometry
    Belov, ME
    Gorshkov, MV
    Udseth, HR
    Smith, RD
    [J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2001, 12 (12) : 1312 - 1319
  • [9] Design and performance of an ESI interface for selective external ion accumulation coupled to a Fourier transform ion cyclotron mass spectrometer
    Belov, ME
    Nikolaev, EN
    Anderson, GA
    Udseth, HR
    Conrads, TP
    Veenstra, TD
    Masselon, CD
    Gorshkov, MV
    Smith, RD
    [J]. ANALYTICAL CHEMISTRY, 2001, 73 (02) : 253 - 261
  • [10] Electron capture dissociation of multiply-charged oxygenated cations. A nonergodic process
    Cerda, BA
    Horn, DM
    Breuker, K
    Carpenter, BK
    McLafferty, FW
    [J]. EUROPEAN MASS SPECTROMETRY, 1999, 5 (05): : 335 - 338
12345678910