Generation and intramolecular cyclization of difluoroalkyl radicals via single electron transfer from the benzeneselenolate anion: Synthesis or alpha,alpha-dinuoro-gamma-lactams

被引：17

作者：

Uneyama, K

Yanagiguchi, T

Asai, H

机构：

[1] Department of Applied Chemistry, Faculty of Engineering, Okayama University

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 44期

关键词：

D O I：

10.1016/S0040-4039(97)10073-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several alpha,alpha-difluoro-gamma-lactams (2) were prepared by radical cyclization of amides (1) which were initiated by a single electron transfer (SET) process from the benzeneselenolate anion. Deselenation of these lactams (2) gave the corresponding alpha,alpha-difluoro-beta-exomethylene lactams (8). (C) 1997 Elsevier Science Ltd.

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页码：7763 / 7764

页数：2

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