A novel microstep device for the size separation of cells

被引：15

作者：

Vankrunkelsven, S

Clicq, D

Pappaert, K

Ranson, W

De Tandt, C

Ottevaere, H

Thienpont, H

Baron, GV

Desmet, G

机构：

[1] Free Univ Brussels, Dept Chem Engn, CHIS, TW, B-1050 Brussels, Belgium

[2] Free Univ Brussels, Dept Elect, B-1050 Brussels, Belgium

[3] Free Univ Brussels, Dept Appl Phys & Photon, B-1050 Brussels, Belgium

来源：

ELECTROPHORESIS | 2004年 / 25卷 / 10-11期

关键词：

microchannels; shear-driven flow; size separation;

D O I：

10.1002/elps.200405900

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We report on a series of preliminary experiments investigating the applicability of a novel method for the size separation of nano- and microsized particles and cells. The working principle is based on the application of a shear-driven flow through stepwise tapered micro- or nanochannels. Size separations of mixtures of 0.5 and 1.0 mum carboxylated polystyrene beads as well as of binary mixtures of Staphylococcus aureus and Saccharomyces cerevisiae cells and of S. cerevisiae and Escherichia coli cells are demonstrated.

引用

收藏

页码：1714 / 1722

页数：9

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