Modulating chemokines: more lessons from viruses

被引:98
作者
Lalani, AS [1 ]
Barrett, JW
McFadden, G
机构
[1] Univ Calif San Francisco, Dept Microbiol & Immunol, Howard Hughes Med Inst, San Francisco, CA 94143 USA
[2] Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6G 2V4, Canada
[3] John P Robarts Res Inst, London, ON N6G 2V4, Canada
来源
IMMUNOLOGY TODAY | 2000年 / 21卷 / 02期
基金
英国医学研究理事会;
关键词
D O I
10.1016/S0167-5699(99)01556-X
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Chemokines are crucial effector molecules involved in orchestrating the host inflammatory response against invading pathogens. Viruses have devised several strategies for exploiting ou neutralizing chemokines or their receptors fn further their own propagation or elude host defenses. Insight info strategies used by viruses fr, modulate chemokines might help generate novel approaches for treating viral diseases and chemokine-mediated inflammatory disorders.
引用
收藏
页码:100 / 106
页数:7
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