Regio- and stereoselective hydrosilylation of terminal alkynes using Grubbs' first-generation olefin-metathesis catalyst

被引：56

作者：

Aricó, CS ^{[1
]}

Cox, LR ^{[1
]}

机构：

[1] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2004年 / 2卷 / 18期

关键词：

D O I：

10.1039/b409832c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Grubbs' first-generation, Ru metathesis complex 3 catalyses the hydrosilylation of terminal alkynes. The reaction exhibits an interesting selectivity profile that is dependent on the reaction concentration and more importantly on the silane employed.

引用

页码：2558 / 2562

页数：5

共 52 条

[1] Mechanism and activity of ruthenium olefin metathesis catalysts: The role of ligands and substrates from a theoretical perspective [J].

Adlhart, C ;

Chen, P .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (11) :3496-3510

[2] Non-metathetic behavior patterns of Grubbs' carbene [J].

Alcaide, B ;

Almendros, P .

CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (06) :1259-1262

[3]

Armstrong SK, 1998, J CHEM SOC PERK T 1, P371

[4] Asymmetric allylboration and ring closing alkene metathesis: A novel strategy for the synthesis of glycosphingolipids [J].

Barrett, AGM ;

Beall, JC ;

Braddock, DC ;

Flack, K ;

Gibson, VC ;

Salter, MM .

JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (20) :6508-6514

[5] VINYLSILANE-TERMINATED AND ALKYNYLSILANE-TERMINATED CYCLIZATION REACTIONS [J].

BLUMENKOPF, TA ;

OVERMAN, LE .

CHEMICAL REVIEWS, 1986, 86 (05) :857-873

[6] SELECTIVITY AND MECHANISM IN CATALYTIC ASYMMETRIC-SYNTHESIS [J].

BROWN, JM .

CHEMICAL SOCIETY REVIEWS, 1993, 22 (01) :25-41

[7] HOMOGENEOUS CATALYSIS .2. MECHANISM OF HYDROSILATION OF OLEFINS CATALYZED BY GROUP 8 METAL COMPLEXES [J].

CHALK, AJ ;

HARROD, JF .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1965, 87 (01) :16-&

[8]

CHAN TH, 1979, SYNTHESIS-STUTTGART, P761

[9] A simple method to polyhydroxylated olefinic molecules using ring-closing olefin metathesis [J].

Chang, SB ;

Grubbs, RH .

TETRAHEDRON LETTERS, 1997, 38 (27) :4757-4760

[10] Synthesis of functionalized olefins by cross and ring-closing metatheses [J].

Chatterjee, AK ;

Morgan, JP ;

Scholl, M ;

Grubbs, RH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (15) :3783-3784

← 1 2 3 4 5 6 →