Assaying hematopoiesis using zebrafish

被引：32

作者：

Boatman, Sonja ^{[1
,2
]}

Barrett, Francesca ^{[1
,2
]}

Satishchandran, Sruthi ^{[1
,2
]}

Jing, Lili ^{[1
,2
]}

Shestopalov, Ilya ^{[1
,2
]}

Zon, Leonard I. ^{[1
,2
,3
]}

机构：

[1] Harvard Univ, Sch Med, Childrens Hosp Boston, Stem Cell Program, Boston, MA 02114 USA

[2] Harvard Univ, Sch Med, Childrens Hosp Boston, Div Hematol Oncol, Boston, MA USA

[3] Howard Hughes Med Inst, Chevy Chase, MD USA

来源：

BLOOD CELLS MOLECULES AND DISEASES | 2013年 / 51卷 / 04期

关键词：

Zebrafish; Hematopoiesis; Stem cell; Screens; Transplantation; CELL TRANSPLANTATION; ADULT HEMATOPOIESIS; GENETIC SCREEN; TIF1-GAMMA; PROSTAGLANDIN-E2; SPECIFICATION; ELONGATION; MIGRATION; PARADIGM; MUTANTS;

D O I：

10.1016/j.bcmd.2013.07.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The zebrafish has become a commonly used model for studying hematopoiesis as a result of its unique attributes. Zebrafish are highly suitable for large-scale genetic and chemical screens compared to other vertebrate systems. It is now possible to analyze hematopoietic lineages in zebrafish and validate cell function via transplantation assays. Here, we review advancements over the past decade in forward genetic screens, chemical screens, fluorescence-activated cell sorting analysis, and transplantation assays. Integrating these approaches enables new chemical and genetic screens that assay cell function within the hematopoietic system. Studies in zebrafish will continue to contribute and expand our knowledge about hematopoiesis, and develop novel treatments for clinical applications. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：271 / 276

页数：6

共 41 条

[31] The Zebrafish moonshine gene encodes transcriptional intermediary factor 1γ, an essential regulator of hematopoiesis [J].

Ransom, DG ;

Bahary, N ;

Niss, K ;

Traver, D ;

Burns, C ;

Trede, NS ;

Paffett-Lugassy, N ;

Saganic, WJ ;

Lim, CA ;

Hersey, C ;

Zhou, Y ;

Barut, BA ;

Lin, S ;

Kingsley, PD ;

Palis, J ;

Orkin, SH ;

Zon, LI .

PLOS BIOLOGY, 2004, 2 (08) :1188-1196

[32]

Ransom DG, 1996, DEVELOPMENT, V123, P311

[33] Targeted gene disruption in somatic zebrafish cells using engineered TALENs [J].

Sander, Jeffry D. ;

Cade, Lindsay ;

Khayter, Cyd ;

Reyon, Deepak ;

Peterson, Randall T. ;

Joung, J. Keith ;

Yeh, Jing-Ruey J. .

NATURE BIOTECHNOLOGY, 2011, 29 (08) :697-698

[34] High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia [J].

Smith, Alexandra C. H. ;

Raimondi, Aubrey R. ;

Salthouse, Chris D. ;

Ignatius, Myron S. ;

Blackburn, Jessica S. ;

Mizgirev, Igor V. ;

Storer, Narie Y. ;

de Jong, Jill L. O. ;

Chen, Aye T. ;

Zhou, Yi ;

Revskoy, Sergei ;

Zon, Leonard I. ;

Langenau, David M. .

BLOOD, 2010, 115 (16) :3296-3303

[35] Cellular Dissection of Zebrafish Hematopoiesis [J].

Stachura, David L. ;

Traver, David .

ZEBRAFISH: CELLULAR AND DEVELOPMENTAL BIOLOGY, PT B, THIRD EDITION, 2011, 101 :75-110

[36] The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis [J].

Thompson, MA ;

Ransom, DG ;

Pratt, SJ ;

MacLennan, H ;

Kieran, MW ;

Detrich, HW ;

Vail, B ;

Huber, TL ;

Paw, B ;

Brownlie, AJ ;

Oates, AC ;

Fritz, A ;

Gates, MA ;

Amores, A ;

Bahary, N ;

Talbot, WS ;

Her, H ;

Beier, DR ;

Postlethwait, JH ;

Zon, LI .

DEVELOPMENTAL BIOLOGY, 1998, 197 (02) :248-269

[37] Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation [J].

Traver, D ;

Winzeler, A ;

Stern, HM ;

Mayhall, EA ;

Langenau, DM ;

Kutok, JL ;

Look, AT ;

Zon, LI .

BLOOD, 2004, 104 (05) :1298-1305

[38] Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants [J].

Traver, D ;

Paw, BH ;

Poss, KD ;

Penberthy, WT ;

Lin, S ;

Zon, LI .

NATURE IMMUNOLOGY, 2003, 4 (12) :1238-1246

[39] Transparent adult zebrafish as a tool for in vivo transplantation analysis [J].

White, Richard Mark ;

Sessa, Anna ;

Burke, Christopher ;

Bowman, Teresa ;

LeBlanc, Jocelyn ;

Ceol, Craig ;

Bourque, Caitlin ;

Dovey, Michael ;

Goessling, Wolfram ;

Burns, Caroline Erter ;

Zon, Leonard I. .

CELL STEM CELL, 2008, 2 (02) :183-189

[40] AML1-ETO mediates hematopoietic self-renewal and leukemogenesis through a COX/β-catenin signaling pathway [J].

Zhang, Yiyun ;

Wang, Jianfeng ;

Wheat, Justin ;

Chen, Xi ;

Jin, Shan ;

Sadrzadeh, Hossein ;

Fathi, Amir T. ;

Peterson, Randall T. ;

Kung, Andrew L. ;

Sweetser, David A. ;

Yeh, Jing-Ruey Joanna .

BLOOD, 2013, 121 (24) :4906-4916

← 1 2 3 4 5 →