Fast diastereoselective Baylis-Hillman reaction by nitroalkenes: synthesis of di- and triene derivatives

被引：21

作者：

Ballini, R ^{[1
]}

Barboni, L ^{[1
]}

Bosica, G ^{[1
]}

Fiorini, D ^{[1
]}

Mignini, E ^{[1
]}

Palmieri, A ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

TETRAHEDRON | 2004年 / 60卷 / 23期

关键词：

D O I：

10.1016/j.tet.2004.04.030

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Baylis-Hillman reaction is performed using nitroalkenes as activated alkenes, ethyl-2-bromomethylacrylate as electrophilic acceptor and DBU as catalyst base. Nitro dienes are obtained in good yields and very short reaction times. Moreover, starting from appropriate nitroalkenes it is possible to realize one pot the synthesis of trienic systems. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：4995 / 4999

页数：5

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