Michael addition of nitroalkanes to dimethyl citraconate, with DBU as base: An unexpected, one-pot synthesis of polyfunctionalized carbonyl derivatives

被引：9

作者：

Ballini, R

Barboni, L

Bosica, G

Fiorini, D

Gil, MV

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

[2] Univ Extremadura, Fac Ciencias, Dept Quim Organ, E-06071 Badajoz, Spain

来源：

SYNLETT | 2002年 / 10期

关键词：

DBU; Nef reaction; keto esters; nitroalkanes; dimethyl citraconate;

D O I：

10.1055/s-2002-34209

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Michael addition of nitroalkanes to dimethyl citraconate, with DBU as base, allows the one pot formation of keto diesters. The reaction proceeds through an equilibrium form of the acceptor, followed by Michael addition of the nitroalkane and then, in situ Nef conversion.

引用

收藏

页码：1706 / 1708

页数：3

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