Evaluation of a high-dose Dexamethasone-eluting stent

被引：38

作者：

Hoffmann, R

Langenberg, R

Radke, P

Franke, A

Blindt, R

Ortlepp, J

Popma, JJ

Weber, C

Hanrath, P

机构：

[1] Univ RWTH Aachen, Med Clin 1, D-52057 Aachen, Germany

[2] Brigham & Womens Hosp, Angiograph Core Lab, Boston, MA USA

[3] Univ Aachen, Dept Biol Mol, Aachen, Germany

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 94卷 / 02期

关键词：

D O I：

10.1016/j.amjcard.2004.03.061

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study evaluated the safety and efficacy of a dexamethasone-eluting stent with a special high dexamethasone-loading dose for treatment of de novo coronary lesions in 30 patients. Eight patients had in-stent restenosis (restenosis rate 31%) at 6-month follow-up, and the in-stent late lumen loss was 0.96 +/- 0.63 mm due to an average intimal hyperplasia area obstruction of 32 +/- 21%, indicating that high-dose dexamethasone-loaded stents do not significantly reduce neointimal proliferation. (C) 2004 by Excerpta Medica, Inc.

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收藏

页码：193 / 195

页数：3

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