Prevalence of antibiotic resistance in anaerobic bacteria: Worrisome developments

被引:114
作者
Hecht, DW
机构
[1] Loyola Univ, Med Ctr, Dept Med, Maywood, IL 60153 USA
[2] US Dept Vet Affairs, Vet Affairs Edward Hines Jr Hosp, Hines, IL 60141 USA
关键词
D O I
10.1086/421558
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Antibiotic-resistant anaerobic bacteria have become increasingly recognized as a confounding factor in the selection of therapeutic agents. The use of potent, broad-spectrum antibiotics as empirical therapy, along with appropriate adjunctive measures, has, in some ways, masked the magnitude of the antibiotic resistance problem that parallels that observed for nonanaerobic pathogens. The use of standardized testing methods that recognize resistance and an understanding of resistance mechanisms have become essential for the treatment of patients and the development of new agents.
引用
收藏
页码:92 / 97
页数:6
相关论文
共 47 条
[31]   A SILENT CARBAPENEMASE GENE IN STRAINS OF BACTEROIDES-FRAGILIS CAN BE EXPRESSED AFTER A ONE-STEP MUTATION [J].
PODGLAJEN, I ;
BREUIL, J ;
BORDON, F ;
GUTMANN, L ;
COLLATZ, E .
FEMS MICROBIOLOGY LETTERS, 1992, 91 (01) :21-29
[32]   TRANSFER OF MULTIPLE ANTIBIOTIC-RESISTANCE BETWEEN SUBSPECIES OF BACTEROIDES-FRAGILIS [J].
PRIVITERA, G ;
DUBLANCHET, A ;
SEBALD, M .
JOURNAL OF INFECTIOUS DISEASES, 1979, 139 (01) :97-101
[33]   Antimicrobial resistance in anaerobes [J].
Rasmussen, BA ;
Bush, K ;
Tally, FP .
CLINICAL INFECTIOUS DISEASES, 1997, 24 :S110-S120
[34]   Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones [J].
Ricci, V ;
Piddock, L .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2003, 52 (04) :605-609
[35]   CLONING AND CHARACTERIZATION OF THE ENDOGENOUS CEPHALOSPORINASE GENE, CEPA, FROM BACTEROIDES-FRAGILIS REVEALS A NEW SUBGROUP OF AMBLER CLASS-A BETA-LACTAMASES [J].
ROGERS, MB ;
PARKER, AC ;
SMITH, CJ .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (11) :2391-2400
[36]   Evidence for extensive resistance gene transfer among Bacteroides spp. and among Bacteroides and other genera in the human colon [J].
Shoemaker, NB ;
Vlamakis, H ;
Hayes, K ;
Salyers, AA .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (02) :561-568
[37]   National survey on the susceptibility of Bacteroides fragilis group:: Report and analysis of trends for 1997-2000 [J].
Snydman, DR ;
Jacobus, NV ;
McDermott, LA ;
Ruthazer, R ;
Goldstein, EJC ;
Finegold, SM ;
Harrell, LJ ;
Hecht, DW ;
Jenkins, SG ;
Pierson, C ;
Venezia, R ;
Rihs, J ;
Gorbach, SL .
CLINICAL INFECTIOUS DISEASES, 2002, 35 :S126-S134
[38]   Multicenter study of in vitro susceptibility of the Bacteroides fragilis group, 1995 to 1996, with comparison of resistance trends from 1990 to 1996 [J].
Snydman, DR ;
Jacobus, NV ;
McDermott, LA ;
Supran, S ;
Cuchural, GJ ;
Finegold, S ;
Harrell, L ;
Hecht, DW ;
Iannini, P ;
Jenkins, S ;
Pierson, C ;
Rihs, J ;
Gorbach, SL .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (10) :2417-2422
[39]   Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections [J].
Solomkin, JS ;
Mazuski, JE ;
Baron, EJ ;
Sawyer, RG ;
Nathens, AB ;
DiPiro, JT ;
Buchman, T ;
Dellinger, EP ;
Jernigan, J ;
Gorbach, S ;
Chow, AW ;
Bartlett, J .
CLINICAL INFECTIOUS DISEASES, 2003, 37 (08) :997-1005
[40]   PLASMID-MEDIATED, TRANSFERABLE RESISTANCE TO CLINDAMYCIN AND ERYTHROMYCIN IN BACTEROIDES-FRAGILIS [J].
TALLY, FP ;
SNYDMAN, DR ;
GORBACH, SL ;
MALAMY, MH .
JOURNAL OF INFECTIOUS DISEASES, 1979, 139 (01) :83-88