Gene expression - RNA interference in adult mice

被引:831
作者
McCaffrey, AP [1 ]
Meuse, L
Pham, TTT
Conklin, DS
Hannon, GJ
Kay, MA
机构
[1] Stanford Univ, Sch Med, Dept Pediat, Stanford, CA 94305 USA
[2] Stanford Univ, Sch Med, Dept Genet, Stanford, CA 94305 USA
[3] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1038/418038a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:38 / 39
页数:2
相关论文
共 9 条
  • [1] Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses
    Bitko V.
    Barik S.
    [J]. BMC Microbiology, 1 (1) : 1 - 11
  • [2] Replication of the human hepatitis delta virus genome is initiated in mouse hepatocytes following intravenous injection of naked DNA or RNA sequences
    Chang, JH
    Sigal, LJ
    Lerro, A
    Taylor, J
    [J]. JOURNAL OF VIROLOGY, 2001, 75 (07) : 3469 - 3473
  • [3] Visualizing gene expression in living mammals using a bioluminescent reporter
    Contag, CH
    Spilman, SD
    Contag, PR
    Oshiro, M
    Eames, B
    Dennery, P
    Stevenson, DK
    Benaron, DA
    [J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1997, 66 (04) : 523 - 531
  • [4] Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    Elbashir, SM
    Harborth, J
    Lendeckel, W
    Yalcin, A
    Weber, K
    Tuschl, T
    [J]. NATURE, 2001, 411 (6836) : 494 - 498
  • [5] Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
    Liu, F
    Song, YK
    Liu, D
    [J]. GENE THERAPY, 1999, 6 (07) : 1258 - 1266
  • [6] Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    Paddison, PJ
    Caudy, AA
    Bernstein, E
    Hannon, GJ
    Conklin, DS
    [J]. GENES & DEVELOPMENT, 2002, 16 (08) : 948 - 958
  • [7] Expanding small RNA interference
    Tuschl, T
    [J]. NATURE BIOTECHNOLOGY, 2002, 20 (05) : 446 - 448
  • [8] Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system
    Yant, SR
    Meuse, L
    Chiu, W
    Ivics, Z
    Izsvak, Z
    Kay, MA
    [J]. NATURE GENETICS, 2000, 25 (01) : 35 - 41
  • [9] High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA
    Zhang, GF
    Budker, V
    Wolff, JA
    [J]. HUMAN GENE THERAPY, 1999, 10 (10) : 1735 - 1737