Stereoselective synthesis of (-)-cytoxazone

被引：35

作者：

Carda, M ^{[1
]}

González, F

Sánchez, R

Marco, JA

机构：

[1] Univ Jaume 1, Dept Quim Organ & Inorgan, E-12080 Castellon de La Plana, Spain

[2] Univ Valencia, Dept Quim Organ, E-46100 Valencia, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2002年 / 13卷 / 09期

关键词：

D O I：

10.1016/S0957-4166(02)00227-6

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The stereoselective synthesis of the cytokine modulator (-)-cytoxazone in enantiopure form is described. Key steps of the process are a syn-stereoselective aldol addition of a chiral ketone mediated by chlorodicyclohexylborane, and a Curtius rearrangement. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：1005 / 1010

页数：6

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