Enhanced histone acetylation and transcription: A dynamic perspective

被引：365

作者：

Clayton, Alison L. ^{[1
]}

Hazzalin, Catherine A. ^{[1
]}

Mahadevan, Louis C. ^{[1
]}

机构：

[1] Univ Oxford, Nucl Signalling Lab, Dept Biochem, Oxford OX1 3QU, England

来源：

MOLECULAR CELL | 2006年 / 23卷 / 03期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/j.molcel.2006.06.017

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Stably enhanced histone acetylation has long been regarded as a condition of transcriptionally active genes. Recent papers suggest a more dynamic model, with rapid turnover of acetylation observed at nontranscribing "poised" genes and shown to be an important determinant of transcriptional efficiency upon gene induction. Are these "special cases," restricted to specific genes and specific types of histone modifications, or could the entire panoply of histone modifications associated with transcription now be revisited with a much more dynamic perspective?

引用

页码：289 / 296

页数：8

共 77 条

[31] Dynamics of global histone acetylation and deacetylation in vivo: rapid restoration of normal histone acetylation status upon removal of activators and repressors [J].

Katan-Khaykovich, Y ;

Struhl, K .

GENES & DEVELOPMENT, 2002, 16 (06) :743-752

[32] Cotranscriptional Set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex [J].

Keogh, MC ;

Kurdistani, SK ;

Morris, SA ;

Ahn, SH ;

Podolny, V ;

Collins, SR ;

Schuldiner, M ;

Chin, KY ;

Punna, T ;

Thompson, NJ ;

Boone, C ;

Emili, A ;

Weissman, JS ;

Hughes, TR ;

Strahl, BD ;

Grunstein, M ;

Greenblatt, JF ;

Buratowski, S ;

Krogan, NJ .

CELL, 2005, 123 (04) :593-605

[33]

KIJIMA M, 1993, J BIOL CHEM, V268, P22429

[34] Histone acetylases and deacetylases in cell proliferation [J].

Kouzarides, T .

CURRENT OPINION IN GENETICS & DEVELOPMENT, 1999, 9 (01) :40-48

[35] MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300 [J].

Li, QJ ;

Yang, SH ;

Maeda, Y ;

Sladek, FM ;

Sharrocks, AD ;

Martins-Green, M .

EMBO JOURNAL, 2003, 22 (02) :281-291

[36] Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome [J].

Liang, GN ;

Lin, JCY ;

Wei, VV ;

Yoo, C ;

Cheng, JC ;

Nguyen, CT ;

Weisenberger, DJ ;

Egger, G ;

Takai, D ;

Gonzales, FA ;

Jones, PA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (19) :7357-7362

[37] Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci [J].

Litt, MD ;

Simpson, M ;

Recillas-Targa, F ;

Prioleau, MN ;

Felsenfeld, G .

EMBO JOURNAL, 2001, 20 (09) :2224-2235

[38] Correlation between histone lysine methylation and developmental changes at the chicken β-globin locus [J].

Litt, MD ;

Simpson, M ;

Gaszner, M ;

Allis, CD ;

Felsenfeld, G .

SCIENCE, 2001, 293 (5539) :2453-2455

[39] Bromodomains in living cells participate in deciphering the histone code [J].

Loyola, A ;

Almouzni, G .

TRENDS IN CELL BIOLOGY, 2004, 14 (06) :279-281

[40]

Marks Paul A, 2004, Novartis Found Symp, V259, P269

← 1 2 3 4 5 6 7 8 →