Enantioselective hydrolysis of (RS)-isopropylideneglycerol acetate with Kluyveromyces marxianus

被引：20

作者：

Molinari, F

Cavenago, KS

Romano, A

Romano, D

Gandolfi, R

机构：

[1] Univ Milan, Dipartimento Sci & Tecnol Alimentari & Microbiol, Sez Microbiol Ind, I-20133 Milan, Italy

[2] Ist Chim Organ Alessandro Marchesini, Fac Farm, I-20133 Milan, Italy

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 12期

关键词：

D O I：

10.1016/j.tetasy.2004.05.010

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The hydrolysis of (RS)-isopropylideneglycerol acetate with whole cells of the yeast Kluyveromyces marxianus is reported. The biotransformation furnished (R)-isopropylideneglycerol as major enantiomer with good enantioselectivity (E = 28) Under optimised conditions. The reaction call be performed in an ultrafiltration-membrane reactor allowing for the obtainment of 19.2g/L of enantiomerically pure (R)-isopropylideneglycerol acetate starting from 60 g/L of racemic mixture. (C) 2004 Elsevier Ltd. All rights reserved.

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页码：1945 / 1947

页数：3

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