Pseudomonas cepacia lipase mediated amidation of benzyl esters

被引：23

作者：

Adamczyk, M

Grote, J

机构：

[1] Department of Chemistry (D9NM), Abbott Diagnostics Division, Abbott Laboratories, Abbott Park, IL 60064-3500

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 44期

关键词：

D O I：

10.1016/0040-4039(96)01792-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Although lipases have been known for some time as catalysts useful for regioselective transesterification or hydrolysis, studies regarding their use as ester amidation catalysts are limited. We have found that the lipase from Pseudomonas cepacia catalyzes amidation reactions with benzyl esters, producing high yields of amides with a variety of different amines. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：7913 / 7916

页数：4

共 26 条

[11] SYNTHESIS OF OPTICALLY-ACTIVE AMIDES FROM BETA-FURYL AND BETA-PHENYL ESTERS BY WAY OF ENZYMATIC AMINOLYSIS [J].

GOTOR, V ;

MENENDEZ, E ;

MOULOUNGUI, Z ;

GASET, A .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1993, (20) :2453-2456

[12] ENZYMATIC RESOLUTION OF RACEMIC AMINES - CRUCIAL ROLE OF THE SOLVENT [J].

KITAGUCHI, H ;

FITZPATRICK, PA ;

HUBER, JE ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (08) :3094-3095

[13]

KLIBANOV A M, 1986, Chemtech, V16, P354

[14] ASYMMETRIC TRANSFORMATIONS CATALYZED BY ENZYMES IN ORGANIC-SOLVENTS [J].

KLIBANOV, AM .

ACCOUNTS OF CHEMICAL RESEARCH, 1990, 23 (04) :114-120

[15] ENZYMATIC CATALYSIS IN ANHYDROUS ORGANIC-SOLVENTS [J].

KLIBANOV, AM .

TRENDS IN BIOCHEMICAL SCIENCES, 1989, 14 (04) :141-144

[16] LIPASE-CATALYZED SYNTHESIS OF OPTICALLY-ACTIVE AMIDES IN ORGANIC MEDIA [J].

QUIROS, M ;

SANCHEZ, VM ;

BRIEVA, R ;

REBOLLEDO, F ;

GOTOR, V .

TETRAHEDRON-ASYMMETRY, 1993, 4 (06) :1105-1112

[17] EFFECT OF THE SOLVENT ON ENZYME REGIOSELECTIVITY [J].

RUBIO, E ;

FERNANDEZMAYORALES, A ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1991, 113 (02) :695-696

[18]

SANCHEZ V, 1994, SYNLETT, P529

[19] INVERSION OF ENZYME ENANTIOSELECTIVITY MEDIATED BY THE SOLVENT [J].

TAWAKI, S ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (05) :1882-1884

[20] MARKED DEPENDENCE OF ENZYME PROCHIRAL SELECTIVITY ON THE SOLVENT [J].

TERRADAS, F ;

TESTONHENRY, M ;

FITZPATRICK, PA ;

KLIBANOV, AM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (02) :390-396

← 1 2 3 →