Iterative amination strategy in the synthesis of peptidomimetics

被引：6

作者：

Frost, CG

Mendonca, P

机构：

[1] School of Chemistry, University of Bath, Bath BA2 7AY, Claverton Down

来源：

CHEMISTRY LETTERS | 1997年 / 11期

关键词：

D O I：

10.1246/cl.1997.1159

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An iterative palladium catalysed cross-coupling reaction of aryl bromides with amines has been employed in the preparation of novel peptidomimetics. This is a versatile strategy with which we can demonstrate the principle of library synthesis by using a diverse range of coupling partners.

引用

页码：1159 / 1160

页数：2

共 15 条

[1] [Anonymous], ANGEW CHEM INT EDIT, DOI DOI 10.1002/ANIE.199622881
[2] First palladium-catalyzed aminations of aryl chlorides
Beller, M
Riermeier, TH
Reisinger, CP
Herrmann, WA
[J]. TETRAHEDRON LETTERS, 1997, 38 (12) : 2073 - 2074
[3] BELLER M, 1995, ANGEW CHEM INT EDIT, V34, P1317
[4] A second-generation catalyst for aryl halide amination: Mixed secondary amines from aryl halides and primary amines catalyzed by (DPPF)PdCl2
Driver, MS
Hartwig, JF
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (30) : 7217 - 7218
[5] GURAM AS, 1995, ANGEW CHEM INT EDIT, V34, P1348, DOI 10.1002/anie.199513481
[6] PALLADIUM-CATALYZED AROMATIC AMINATIONS WITH IN-SITU GENERATED AMINOSTANNANES
GURAM, AS
BUCHWALD, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (17) : 7901 - 7902
[7] Palladium-catalyzed amination of aryl halides: Mechanism and rational catalyst design
Hartwig, JF
[J]. SYNLETT, 1997, (04) : 329 - +
[8] PEPTOIDS - A NEW APPROACH TO THE DEVELOPMENT OF PHARMACEUTICALS
KESSLER, H
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1993, 32 (04): : 543 - 544
[9] PALLADIUM-CATALYZED AROMATIC AMINATION OF ARYL BROMIDES WITH N,N-DIETHYLAMINO-TRIBUTYLTIN
KOSUGI, M
KAMEYAMA, M
MIGITA, T
[J]. CHEMISTRY LETTERS, 1983, (06) : 927 - 928
[10] PALLADIUM-CATALYZED SYNTHESIS OF ARYLAMINES FROM ARYL HALIDES - MECHANISTIC STUDIES LEAD TO COUPLING IN THE ABSENCE OF TIN REAGENTS
LOUIE, J
HARTWIG, JF
[J]. TETRAHEDRON LETTERS, 1995, 36 (21) : 3609 - 3612

← 1 2 →