LGICdb:: a manually curated sequence database after the genomes

被引:20
作者
Donizelli, Marco [1 ]
Djite, Marie-Ange [1 ]
Le Novere, Nicolas [1 ]
机构
[1] EMBL, European Bioinformat Inst, Hinxton CB10 1SD, England
关键词
D O I
10.1093/nar/gkj104
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Ligand-gated ion channels form transmembrane ionic pores controlled by the binding of chemicals. The LGICdb aims to be a non-redundant, manually curated resource offering access to the large number of subunits composing extracellularly activated ligand gated ion channels, such as nicotinic, ATP, GABA and glutamate ionotropic receptors. Composed of more than 500 human curated entries, the XML native database has been relocated in 2004 to the EBI. Its facilities have been enhanced with a new search system, customized multiple sequence alignments and manipulation of protein structures (http://www.ebi.ac.uk/compneur-srv/LGICdb/). Despite the vast improvement of general sequence resources, the LGICdb still provide sequences unavailable elsewhere.
引用
收藏
页码:D267 / D269
页数:3
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