Recovery mechanism of the antioxidant activity from carnosic acid quinone, an oxidized sage and rosemary antioxidant

被引：52

作者：

Masuda, T ^{[1
]}

Inaba, Y

Maekawa, T

Takeda, Y

Tamura, H

Yamaguchi, H

机构：

[1] Univ Tokushima, Fac Integrated Arts & Sci, Tokushima 7708502, Japan

[2] Univ Ryukyus, Trop Biosphere Res Ctr, Okinawa 9071541, Japan

[3] Osaka City Univ, Grad Sch Human Life Sci, Osaka 5588585, Japan

[4] Kagawa Univ, Fac Agr, Miki, Kagawa 7610701, Japan

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2002年 / 50卷 / 21期

关键词：

carnosic acid quinone; antioxidant mechanism; redox reaction; carnosic acid; carnosol; rosmanol; 7-O-methylrosmanol; sage; rosemary;

D O I：

10.1021/jf025605o

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

A solution of carnosic acid quinone, which is a radical chain-termination product having no antioxidant activity in the antioxidant reaction of carnosic acid, recovers potent antioxidant activity upon standing. The HPLC analysis of an aged solution of carnosic acid quinone revealed that several antioxidants are produced in the solution. From the time-course and quantitative analyses of the formation of the products and their structural analysis, an antioxidant mechanism from carnosic acid quinone is proposed that includes a redox reaction of carnosic acid quinone in addition to the isomerization to lactone derivatives. In the first stage of antioxidation, carnosic acid, the reduction product from carnosic acid quinone, contributes to the potent antioxidant activity of the solution, This proposed mechanism can explain one of the reasons for the strong antioxidant activity of the extract of the popular herbs sage and rosemary.

引用

页码：5863 / 5869

页数：7

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