Trinucleotide repeats and other microsatellites in yeasts

被引：29

作者：

Richard, GF

Hennequin, C

Thierry, A

Dujon, B

机构：

[1] Univ Paris 06, URA 1300 CNRS, UFR 927, Inst Pasteur,Unite Genet Mol Levures, F-75724 Paris 15, France

[2] CHU Amiens, Serv Parasitol Mycol & Med Voyages, F-80054 Amiens, France

来源：

RESEARCH IN MICROBIOLOGY | 1999年 / 150卷 / 9-10期

关键词：

trinucleotide repeats; microsatellites; mycology; replication slippage; recombination;

D O I：

10.1016/S0923-2508(99)00131-X

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Microsatellites are direct tandem DNA repeats found in all genomes. A particular class of microsatellites, called trinucleotide repeats, is responsible for a number of neurological disorders in humans. We review here our current state of knowledge on trinucleotide repeat instability, and discuss the molecular mechanisms that may be involved in trinucleotide repeat expansions leading to fatal diseases in humans. We also present original data on microsatellite distribution in several microbial genomes, and on the use of microsatellites as physical markers to accurately and easily genotype yeast strains. (C) 1999 Editions scientifiques et medicales Elsevier SAS.

引用

页码：589 / 602

页数：14

共 109 条

[41] CTG triplet repeats from the myotonic dystrophy gene are expanded in Escherichia coli distal to the replication origin as a single large event
Kang, S
Ohshima, K
Jaworski, A
Wells, RD
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1996, 258 (04) : 543 - 547
[42] EXPANSION AND DELETION OF CTG REPEATS FROM HUMAN-DISEASE GENES ARE DETERMINED BY THE DIRECTION OF REPLICATION IN ESCHERICHIA-COLI
KANG, S
JAWORSKI, A
OHSHIMA, K
WELLS, RD
[J]. NATURE GENETICS, 1995, 10 (02) : 213 - 218
[43] Trinucleotide repeats and long homopeptides in genes and proteins associated with nervous system disease and development
Karlin, S
Burge, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (04) : 1560 - 1565
[44] COMPARISONS OF EUKARYOTIC GENOMIC SEQUENCES
KARLIN, S
LADUNGA, I
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) : 12832 - 12836
[45] KARLIN S, 1995, TRENDS GENET, V11, P283
[46] Tn10 transposition via a DNA hairpin intermediate
Kennedy, AK
Guhathakurta, A
Kleckner, N
Haniford, DB
[J]. CELL, 1998, 95 (01) : 125 - 134
[47] Ataxin-1 nuclear localization and aggregation:: Role in polyglutamine-induced disease in SCA1 transgenic mice
Klement, IA
Skinner, PJ
Kaytor, MD
Yi, H
Hersch, SM
Clark, HB
Zoghbi, HY
Orr, HT
[J]. CELL, 1998, 95 (01) : 41 - 53
[48] TRINUCLEOTIDE REPEAT AMPLIFICATION AND HYPERMETHYLATION OF A CPG ISLAND IN FRAXE MENTAL-RETARDATION
KNIGHT, SJL
FLANNERY, AV
HIRST, MC
CAMPBELL, L
CHRISTODOULOU, Z
PHELPS, SR
POINTON, J
MIDDLETONPRICE, HR
BARNICOAT, A
PEMBREY, ME
HOLLAND, J
OOSTRA, BA
BOBROW, M
DAVIES, KE
[J]. CELL, 1993, 74 (01) : 127 - 134
[49] Destabilization of yeast micro- and minisatellite DNA sequences by mutations affecting a nuclease involved in Okazaki fragment processing (rad27) and DNA polymerase δ (pol3-t)
Kokoska, RJ
Stefanovic, L
Tran, HT
Resnick, MA
Gordenin, DA
Petes, TD
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (05) : 2779 - 2788
[50] Kuhls K, 1995, MICROBIOL RES, V150, P363

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