Guaiane-type sesquiterpenes from Curcuma wenyujin and their inhibitory effects on nitric oxide production

被引：50

作者：

Lou, Yan ^{[1
]}

Zhao, Feng ^{[2
]}

He, Hao ^{[1
]}

Peng, Kai-Feng ^{[1
]}

Zhou, Xiao-Hua ^{[1
]}

Chen, Li-Xia ^{[1
]}

Qiu, Feng ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Dept Nat Prod Chem, Shenyang 110016, Peoples R China

[2] Yantai Univ, Sch Pharm, Yantai 264005, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2009年 / 11卷 / 08期

关键词：

Curcuma wenyujin; guaiane; sesquiterpenes; nitric oxide; zedoalactone D; E; F; CARABRANE-TYPE SESQUITERPENES; ABSOLUTE STEREOSTRUCTURES; ZEDOARIAE RHIZOMA;

D O I：

10.1080/10286020903042358

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new guaiane-type sesquiterpenes (1S,4S,5S,10R)-zedoarondiol, zedoalactones D, E, and F (1-4), along with 10 known ones (5-14), were isolated from Curcuma wenyujin Y. H. Chen et C. Ling. The structures of these new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1-14 on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated.

引用

页码：737 / 747

页数：11

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