Totally diastereoselective synthesis of a new chiral quinoline diazaphospholidine ligand and its derivatives

被引：16

作者：

Delapierre, G ^{[1
]}

Achard, M ^{[1
]}

Buono, G ^{[1
]}

机构：

[1] ENSSPICAM, UMR 6516 Synthese Catalyse & Chiralite, F-13397 Marseille 20, France

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 22期

关键词：

chiral bidentate P; N ligand; phosphine oxide; phosphine sulphide; iminophosphorane; palladium complex;

D O I：

10.1016/S0040-4039(02)00691-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

QUIPHOS-PN5, a new stable P,N ligand with a stereogenic phosphorus centre was synthesised in two steps from 8-bromoquinoline (61% yield). Its structure and its bidentate chelating ability was confirmed by the X-ray structure of a palladium(II) complex with this ligand. P(V) derivatives of QUIPHOS-PN5 were then easily obtained in excellent yields (85-100%). (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：4025 / 4028

页数：4

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