Iron-catalysed fluoroaromatic coupling reactions under catalytic modulation with 1,2-bis(diphenylphosphino)benzene

被引：85

作者：

Hatakeyama, Takuji ^{[1
]}

Kondo, Yoshiyuki ^{[1
]}

Fujiwara, Yu-ichi ^{[1
]}

Takaya, Hikaru ^{[1
]}

Ito, Shingo ^{[2
]}

Nakamura, Eiichi ^{[2
]}

Nakamura, Masaharu ^{[1
]}

机构：

[1] IRCELS, Inst Chem Res, Kyoto 6110011, Japan

[2] Univ Tokyo, Dept Chem, Bunkyo Ku, Tokyo 1130033, Japan

来源：

CHEMICAL COMMUNICATIONS | 2009年 / 10期

关键词：

SECONDARY ALKYL-HALIDES; CROSS-COUPLINGS; GRIGNARD-REAGENTS; LIQUID-CRYSTALS; ARYLATION; CHLORIDES;

D O I：

10.1039/b820879d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalytic amount of 1,2-bis(diphenylphosphino) benzene (DPPBz) achieves selective cleavage of sp(3)-carbon-halogen bond in the iron-catalysed cross-coupling between polyfluorinated arylzinc reagents and alkyl halides, which was unachievable with a stoichiometric modifier such as TMEDA; the selective iron-catalysed fluoroaromatic coupling provides easy and practical access to poly-fluorinated aromatic compounds.

引用

页码：1216 / 1218

页数：3

共 37 条

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