Dilution-Free Analysis from Picoliter Droplets by Nano-Electrospray Ionization Mass Spectrometry

被引：100

作者：

Kelly, Ryan T. ^{[1
]}

Page, Jason S. ^{[1
]}

Marginean, Ioan ^{[1
]}

Tang, Keqi ^{[1
]}

Smith, Richard D. ^{[1
]}

机构：

[1] Pacific NW Natl Lab, Div Biol Sci, Richland, WA 99352 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 37期

关键词：

mass spectrometry; microdroplets; microfluidics; nanoelectrospray; single cells; SINGLE-CELLS; MICROFLUIDIC DEVICES; ENCAPSULATION; MICRODROPLETS; SEPARATION; PROTEOMICS; ONLINE; VOLUME;

D O I：

10.1002/anie.200902501

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Packaged, transferred, and delivered: A method has been developed that automatically transfers the contents of oil-encapsulated aqueous plugs to a co-flowing aqueous stream, which enables dilution-free electrospray ionization (ESI) mass spectrometric analysis for droplet-based microfluidics. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：6832 / 6835

页数：4

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