The systemic inflammatory response syndrome

被引：151

作者：

Robertson, Charles M. ^{[1
]}

Coopersmith, Craig M. ^{[1
]}

机构：

[1] Washington Univ, Sch Med, Dept Surg, St Louis, MO 63110 USA

来源：

MICROBES AND INFECTION | 2006年 / 8卷 / 05期

关键词：

adaptive immune system; biomarkers; critical illness; hyperinflammatory; hypoinflammatory; inflammation; innate immune system; multiple organ dysfunction syndrome; pathophysiology; sepsis; systemic inflammatory response syndrome;

D O I：

10.1016/j.micinf.2005.12.016

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic intervention in patients with this complex entity. (c) 2006 Elsevier SAS. All rights reserved.

引用

页码：1382 / 1389

页数：8

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