Regulatory regions of smeDEF in Stenotrophomonas maltophilia strains expressing different amounts of the multidrug efflux pump SmeDEF

被引:37
作者
Sanchez, P [1 ]
Alonso, A [1 ]
Martinez, JL [1 ]
机构
[1] CSIC, Ctr Nacl Biotecnol, Dept Biotecnol Microbiana, E-28049 Madrid, Spain
关键词
D O I
10.1128/AAC.48.6.2274-2276.2004
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The smeT-smeDEF region and the smeT gene, which encodes the smeDEF repressor, are highly polymorphic. Few changes in smeT might be associated with smeDEF overexpression. The results obtained with cellular extracts suggest that mutant SmeT proteins cannot bind to the operator and that other transcription factors besides SmeT are involved in the regulation of smeDEF expression.
引用
收藏
页码:2274 / 2276
页数:3
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