Dynamic helical structures: Detection and amplification of chirality

被引：216

作者：

Maeda, Katsuhiro

Yashima, Eiji ^{[1
]}

机构：

[1] Nagoya Univ, Grad Sch Engn, Dept Mol Design & Engn, Chikusa Ku, Nagoya, Aichi 4648603, Japan

[2] JST, ERATO, Yashima Super Struct Helix Project, Moriyama Ku, Nagoya, Aichi 4630003, Japan

来源：

SUPRAMOLECULAR CHIRALITY | 2006年 / 265卷

关键词：

chiral amplification; chirality sensing; helical aggregates; helical macromolecules; helix;

D O I：

10.1007/128_035

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A unique feature of dynamic helical, chromophoric macromolecules that enables the detection of a small imbalance in chiral guest molecules through a noncovalent bonding interaction with high cooperativity is described. In sharp contrast to host-guest and supramolecular systems based on small synthetic receptor molecules, the chiral information of nonracemic guest molecules transfers with a significant amplification in a helical polymer as an excess of a single-handed helix, resulting in a highly efficient chirality-sensing system. Helical aggregates with controlled helicity based on small molecules and their chiral amplification and use in chirality sensing are also briefly described in this review.

引用

页码：47 / 88

页数：42

共 167 条

[21] Chiral architectures from macromolecular building blocks [J].