Increased blood flow in the basal ganglia when using cues to direct attention

被引:18
作者
Koski, L [1 ]
Paus, T [1 ]
Hofle, N [1 ]
Petrides, M [1 ]
机构
[1] Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada
基金
英国医学研究理事会;
关键词
selective attention; visual attention; putamen; orienting; positron emission tomography; human;
D O I
10.1007/s002210050894
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We used positron emission tomography (PET) in ten subjects to study the brain regions involved in voluntary shifts of attention. For six scans, subjects per formed a visual target detection task in which the location of the target was indicated in advance on some proportion of trials by the appearance of an arrow cue at fixation. The informative cues were successful in speeding reaction time to the target. Blood flow in the left putamen was correlated with the proportion of informative cues provided within a scan. We discuss this finding in terms of three possible interpretations: attentional shifts, response inhibition, and motor preparation related to the use of the right hand to respond. Blood flow in: cortical regions commonly associated with attention was not related to cue ratio, a finding that may reflect automatization of the processes involved in interpreting and using the cues.
引用
收藏
页码:241 / 246
页数:6
相关论文
共 28 条
[21]  
ROSEN AC, IN PRESS J COGNITIVE
[22]  
Talairach G., 1988, Planar Stereotaxic Atlas of the Human Brain
[23]   The influence of stimulus location on the brain activation pattern in detection and orientation discrimination - A PET study of visual attention [J].
Vandenberghe, R ;
Dupont, P ;
DeBruyn, B ;
Bormans, G ;
Michiels, J ;
Mortelmans, L ;
Orban, GA .
BRAIN, 1996, 119 :1263-1276
[24]   A metabolic mapping study of orientation discrimination and detection tasks in the cat [J].
Vanduffel, W ;
Vandenbussche, E ;
Singer, W ;
Orban, GA .
EUROPEAN JOURNAL OF NEUROSCIENCE, 1997, 9 (06) :1314-1328
[25]   MRI-PET REGISTRATION WITH AUTOMATED ALGORITHM [J].
WOODS, RP ;
MAZZIOTTA, JC ;
CHERRY, SR .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 1993, 17 (04) :536-546
[26]  
Worsley KJ, 1996, HUM BRAIN MAPP, V4, P58, DOI 10.1002/(SICI)1097-0193(1996)4:1<58::AID-HBM4>3.0.CO
[27]  
2-O
[28]   CORTICOSTRIATAL CONNECTIONS OF EXTRASTRIATE VISUAL AREAS IN RHESUS-MONKEYS [J].
YETERIAN, EH ;
PANDYA, DN .
JOURNAL OF COMPARATIVE NEUROLOGY, 1995, 352 (03) :436-457