The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

被引：720

作者：

Takenawa, Tadaomi ^{[1
]}

Suetsugu, Shiro ^{[1
]}

机构：

[1] Univ Tokyo, Inst Med Sci, Dept Biochem, Minato Ku, Tokyo 1088639, Japan

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2007年 / 8卷 / 01期

关键词：

D O I：

10.1038/nrm2069

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Wiskott-Aldrich syndrome protein (WASP) and WASP-family verprolin-homologous protein (WAVE) family proteins are scaffolds that link upstream signals to the activation of the ARP2/3 complex, leading to a burst of actin polymerization. ARP2/3-complex-mediated actin polymerization is crucial for the reorganization of the actin cytoskeleton at the cell cortex for processes such as cell movement, vesicular trafficking and pathogen infection. Large families of membrane-binding proteins were recently found to interact with WASP and WAVE family proteins, therefore providing a new layer of membrane-dependent regulation of actin polymerization.

引用

页码：37 / 48

页数：12

共 150 条

[41] Enteropathogenic E-coli acts through WASP and Arp2/3 complex to form actin pedestals [J].

Kalman, D ;

Weiner, OD ;

Goosney, DL ;

Sedat, JW ;

Finlay, BB ;

Abo, A ;

Bishop, JW .

NATURE CELL BIOLOGY, 1999, 1 (06) :389-391

[42] A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis [J].

Kamioka, Y ;

Fukuhara, S ;

Sawa, H ;

Nagashima, J ;

Masuda, M ;

Matsuda, M ;

Mochizuki, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (38) :40091-40099

[43] WICH, a novel verprolin homology domain-containing protein that functions cooperatively with N-WASP in actin-microspike formation [J].

Kato, M ;

Miki, H ;

Kurita, S ;

Endo, T ;

Nakagawa, H ;

Miyamoto, S ;

Takenawa, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 291 (01) :41-47

[44] CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation [J].

Kawano, Y ;

Yoshimura, T ;

Tsuboi, D ;

Kawabata, S ;

Kaneko-Kawano, T ;

Shirataki, H ;

Takenawa, T ;

Kaibuchi, K .

MOLECULAR AND CELLULAR BIOLOGY, 2005, 25 (22) :9920-9935

[45] Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein [J].

Kim, AS ;

Kakalis, LT ;

Abdul-Manan, M ;

Liu, GA ;

Rosen, MK .

NATURE, 2000, 404 (6774) :151-158

[46] Phosphorylation of WAVE1 regulates actin polymerization and dendritic spine morphology [J].

Kim, Yong ;

Sung, Jee Young ;

Ceglia, Ilaria ;

Lee, Ko-Woon ;

Ahn, Jung-Hyuck ;

Halford, Jonathan M. ;

Kim, Amie M. ;

Kwak, Seung P. ;

Park, Jong Bae ;

Ryu, Sung Ho ;

Schenck, Annette ;

Bardoni, Barbara ;

Scott, John D. ;

Nairn, Angus C. ;

Greengard, Paul .

NATURE, 2006, 442 (7104) :814-817

[47] Molecular cloning of p125(Nap1), a protein that associates with an SH3 domain of Nck [J].

Kitamura, T ;

Kitamura, Y ;

Yonezawa, K ;

Totty, NF ;

Gout, I ;

Hara, K ;

Waterfield, MD ;

Sakaue, M ;

Ogawa, W ;

Kasuga, M .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1996, 219 (02) :509-514

[48] p140Sra-1 (specifically Rac1-associated protein) is a novel specific target for Rac1 small GTPase [J].

Kobayashi, K ;

Kuroda, S ;

Fukata, M ;

Nakamura, T ;

Nagase, T ;

Nomura, N ;

Matsuura, Y ;

Yoshida-Kubomura, N ;

Iwamatsu, A ;

Kaibuchi, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (01) :291-295

[49] A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells [J].

Krueger, EW ;

Orth, JD ;

Cao, H ;

McNiven, MA .

MOLECULAR BIOLOGY OF THE CELL, 2003, 14 (03) :1085-1096

[50] Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex [J].

Krugmann, S ;

Jordens, I ;

Gevaert, K ;

Driessens, M ;

Vandekerckhove, J ;

Hall, A .

CURRENT BIOLOGY, 2001, 11 (21) :1645-1655

← 1 2 3 4 5 6 7 8 9 10 →