PolymiRTS Database: linking polymorphisms in microRNA target sites with complex traits

被引：117

作者：

Bao, Lei

Zhou, Mi

Wu, Ligang

Lu, Lu

Goldowitz, Dan

Williams, Robert W.

Cui, Yan

机构：

[1] Univ Tennessee, Ctr Hlth Sci, Dept Mol Sci, Memphis, TN 38163 USA

[2] Univ Tennessee, Ctr Hlth Sci, Ctr Genomics & Bioinformat, Memphis, TN 38163 USA

[3] Univ Tennessee, Ctr Hlth Sci, Dept Anat & Neurobiol, Memphis, TN 38163 USA

[4] Univ Tennessee, Ctr Hlth Sci, Dept Pediat, Memphis, TN 38163 USA

[5] NYU, Sch Med, Skirball Inst Biomol Med, New York, NY USA

[6] Nantong Univ, Key Lab Nerve Regenerat, Nantong, Jiangsu, Peoples R China

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/nar/gkl797

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Polymorphism in microRNA Target Site (PolymiRTS) database is a collection of naturally occurring DNA variations in putative microRNA target sites. PolymiRTSs may affect gene expression and cause variations in complex phenotypes. The database integrates sequence polymorphism, phenotype and expression microarray data, and characterizes PolymiRTSs as potential candidates responsible for the quantitative trait locus (QTL) effects. It is a resource for studying PolymiRTSs and their implications in phenotypic variations. PolymiRTS database can be accessed at http://compbio.utmem.edu/miRSNP/.

引用

页码：D51 / D54

页数：4

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