Synthesis of ω-(hetero)arylalkynylated α-amino acid by sonogashira-type reactions in aqueous media

被引：30

作者：

Brea, Roberto J.

Lopez-Deber, M. Pilar

Castedo, Luis

Granja, Juan R. ^{[1
]}

机构：

[1] Univ Santiago, Dept Quim Organ, Santiago De Compostela 15782, Spain

[2] Univ Santiago, Fac Quim, CSIC, Unidada Asociada, Santiago De Compostela 15782, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 20期

关键词：

D O I：

10.1021/jo061300n

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Chemical Equation Presented) Mild conditions are described that allow the palladium-catalyzed cross-coupling of Cα-alkynylated glycine with a wide variety of electron-rich and electron-poor aryl and heteroaryl halides in aqueous media. © 2006 American Chemical Society.

引用

页码：7870 / 7873

页数：4

共 67 条

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