Eurycoma longifolia Jack enhances libido in sexually experienced male rats

被引:31
作者
Ang, HH [1 ]
Sim, MK [1 ]
机构
[1] NATL UNIV SINGAPORE,FAC MED,DEPT PHARMACOL,SINGAPORE 119250,SINGAPORE
关键词
E-longifolia Jack; libido; sexually experienced male rats;
D O I
10.1538/expanim.46.287
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 [兽医学];
摘要
The effects of Eurycoma longifolia Jack were studied on the libido of sexually experienced male rats after dosing them with 200, 400 and 800 mg/kg body weight twice daily of different fractions of E. longifolia Jack for 10 days. Results showed that E. longifolia Jack produced a dose-dependent increase in mounting frequency of the treated animals with 400 mg/kg of chloroform, methanol, water and butanol fractions resulting in mounting frequencies of 5.3 +/- 1.2, 4.9 +/- 0.7, 4.8 +/- 0.7 and 5.2 +/- 0.1, and 800 mg/kg further increased them to 5.4 +/- 0.8, 5.4 +/- 0.8, 5.2 +/- 0.6 and 5.3 +/- 0.2 respectively but there were no erections, intromissions, ejaculations or seminal emissions during the 20-min observation period which allowed for the measurement of sexual arousal reflected by mounting frequency uninfluenced by other behavioural components. This study provides evidence that E. longifolia Jack is a potent stimulator of sexual arousal in sexually Vigorous male rats in the absence of feedback from genital sensation.
引用
收藏
页码:287 / 290
页数:4
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