Stabilization of α-chymotrypsin at air-water interface through surface binding to gold nanoparticle scaffolds

被引：36

作者：

Jordan, Brian J.

Hong, Rui

Gider, Basar

Hill, Jason

Emrick, Todd

Rotello, Vincent M.

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

[2] Univ Massachusetts, Dept Polymer Sci & Engn, Amherst, MA 01003 USA

来源：

SOFT MATTER | 2006年 / 2卷 / 07期

关键词：

D O I：

10.1039/b603980d

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Gold nanoparticles stabilize chymotrypsin (ChT) against denaturation at the air-water interface through catenation and preferential localization of the nanoparticles at the air water interface with concomitant decrease in interfacial energy.

引用

页码：558 / 560

页数：3

共 31 条

[1] Factors affecting short-term and long-term stabilities of proteins (Reprinted from Advanced Drug Delivery Reviews, vol 9, pg 201-237, 1992)
Arakawa, T
Prestrelski, SJ
Kenney, WC
Carpenter, JF
[J]. ADVANCED DRUG DELIVERY REVIEWS, 2001, 46 (1-3) : 307 - 326
[2] Protein adsorption at the oil/water interface: characterization of adsorption kinetics by dynamic interfacial tension measurements
Beverung, CJ
Radke, CJ
Blanch, HW
[J]. BIOPHYSICAL CHEMISTRY, 1999, 81 (01) : 59 - 80
[3] Proteases in organic synthesis
Bordusa, F
[J]. CHEMICAL REVIEWS, 2002, 102 (12) : 4817 - 4867
[4] Immobilizing enzymes: How to create more suitable biocatalysts
Bornscheuer, UT
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (29) : 3336 - 3337
[5] CANTOR CR, 1982, PROTEINS
[6] Highly efficient biocatalysts via covalent immobilization of Candida rugosa lipase on ethylene glycol-modified gold-silica nanocomposites
Drechsler, U
Fischer, NO
Frankamp, BL
Rotello, VM
[J]. ADVANCED MATERIALS, 2004, 16 (03) : 271 - +
[7] Directing self-assembly of nanoparticles at water/oil interfaces
Duan, HW
Wang, DY
Kurth, DG
Möhwald, H
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (42) : 5639 - 5642
[8] Highly efficient "tight fit" immobilization of α-chymotrypsin in mesoporous MCM-41:: A novel approach using precursor immobilization and activation
Fadnavis, NW
Bhaskar, V
Kantam, ML
Choudary, BM
[J]. BIOTECHNOLOGY PROGRESS, 2003, 19 (02) : 346 - 351
[9] Mixed monolayer coverage on gold nanoparticles for interfacial stabilization of immiscible fluids
Glogowski, E
He, JB
Russell, TP
Emrick, T
[J]. CHEMICAL COMMUNICATIONS, 2005, (32) : 4050 - 4052
[10] A simple method for improving protein solubility and long-term stability
Golovanov, AP
Hautbergue, GM
Wilson, SA
Lian, LY
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (29) : 8933 - 8939

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