Mitotic exit: The Cdc14 double cross

被引:28
作者
Geymonat, M [1 ]
Jensen, S [1 ]
Johnston, LH [1 ]
机构
[1] Natl Inst Med Res, Div Yeast Genet, London NW7 1AA, England
关键词
D O I
10.1016/S0960-9822(02)00963-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The release of Cdc14 from the nucleolus occurs in two waves in early and late anaphase, controlled by the FEAR and MEN pathways, respectively. Two new papers report the localisation at the spindle pole body of the Cdc14 released in early anaphase and, surprisingly, show that the two pulses of released Cdc14 have opposite effects on MEN activation.
引用
收藏
页码:R482 / R484
页数:3
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