Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications

被引:586
作者
Qiao, Ruirui [1 ]
Yang, Chunhui [1 ]
Gao, Mingyuan [1 ]
机构
[1] Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China
关键词
INTRAVASCULAR CONTRAST AGENT; MAGNETIC-RESONANCE ANGIOGRAPHY; BLOOD-POOL AGENT; ONE-POT REACTION; TAT PEPTIDE; FOLATE RECEPTOR; CELLULAR UPTAKE; ORGANIC-MATTER; SURFACE CHARACTERISTICS; NC100150; INJECTION;
D O I
10.1039/b902394a
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Superparamagnetic iron oxide nanoparticles have received great attention due to their applications as contrast agents for magnetic resonance imaging (MRI). This feature article briefly introduces the concepts of MRI and MRI contrast agents, and then mainly discusses the synthesis, surface modification, surface functionalization, colloidal stability and biocompatibility of iron oxide particles, followed by their MRI applications.
引用
收藏
页码:6274 / 6293
页数:20
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