Photoacoustic monitoring and imaging of blood vessels in tissue.

被引:1
作者
Kolkman, RGM [1 ]
Pilatou, MC [1 ]
Steenbergen, W [1 ]
de Mul, FFM [1 ]
机构
[1] Univ Twente, Dept Appl Phys, NL-7500 AE Enschede, Netherlands
来源
BIOMEDICAL OPTOACOUSTICS III | 2002年 / 4618卷
关键词
photoacoustics; piezoelectric transducer; tissue; blood; imaging;
D O I
10.1117/12.469850
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
Using very sensitive photoacoustical detectors we localized and monitored the blood content in tissue. In these detectors a PVdF-layer has been used as piezo-electric material and also fibers for the illumination of the sample are integrated. The resolution is about 20 mum in depth and about 50-100 mum laterally. The wavelengths of the laser light were 532 and 1064 run. With these colors we can measure at different depths in tissue. The measurements concerned blood perfusion in real tissue: vessels in chicken breast, in test animals at various positions and in the human arm.
引用
收藏
页码:76 / 80
页数:5
相关论文
共 10 条
[1]   A new theoretical approach to photoacoustic signal generation [J].
Hoelen, CGA ;
de Mul, FFM .
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA, 1999, 106 (02) :695-706
[2]   Image reconstruction for photoacoustic scanning of tissue structures [J].
Hoelen, CGA ;
de Mul, FFM .
APPLIED OPTICS, 2000, 39 (31) :5872-5883
[3]   Photoacoustic Tissue Scanning (PATS) [J].
Hoelen, CGA ;
Kolkman, RGM ;
Letteboer, M ;
Berendsen, R ;
de Mul, FFM .
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF, 1999, 3597 :336-343
[4]  
HOELEN CGA, 1998, SPIE BIOS 98 C STOCK, V3566
[5]  
HOELEN CGA, 1998, OPTICS LETT, V28
[6]   Photo-acoustic A-scanning and monitoring of blood content in tissue [J].
Kolkman, RGM ;
Pilatou, MC ;
Hondebrink, E ;
De Mul, FFM .
BIOMEDICAL OPTOACOUSTICS, 2000, 3916 :76-83
[7]  
KOLKMAN RGM, 1999, ADV OPTICAL IMAGING, P239
[8]   Laser opto-acoustic imaging of the breast: Detection of cancer angiogenesis [J].
Oraevsky, AA ;
Andreev, VA ;
Karabutov, AA ;
Fleming, DR ;
Gatalica, Z ;
Singh, H ;
Esenaliev, RO .
OPTICAL TOMOGRAPHY AND SPECTROSCOPY OF TISSUE III, PROCEEDINGS OF, 1999, 3597 :352-363
[9]  
ORAEVSKY AA, 1999, ADV OPTICAL IMAGIN P, P236
[10]   Photo-acoustic imaging of microvascular structure in tissue [J].
Pilatou, MC ;
Kolkman, RGM ;
Hondebrink, E ;
Berendsen, R ;
De Mul, FFM .
BIOMEDICAL OPTOACOUSTICS, 2000, 3916 :48-54