Synthesis of 7,9-nitrogen-substituted paclitaxel derivatives

被引:6
作者
Appendino, G
Jakupovic, J
Varese, M
Belloro, E
Danieli, B
Bombardelli, E
机构
[1] TECH UNIV BERLIN,INST ORGAN CHEM,D-10623 BERLIN,GERMANY
[2] DIPARTIMENTO CHIM ORGAN & IND,I-20133 MILAN,ITALY
[3] INDENA SPA,I-20141 MILAN,ITALY
关键词
D O I
10.1016/0040-4039(96)01744-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Reaction of 10-deacetyl-10-dehydrobaccatin III-type taxanes with hydrazine afforded 7,9-pyrazoline adducts, which retained anticancer activity. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:7837 / 7840
页数:4
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