Nickel-Catalyzed Three-Component [2+2+2] Cycloaddition Reaction of Arynes, Alkenes, and Alkynes

被引：69

作者：

Qiu, Zaozao

Xie, Zuowei ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 31期

关键词：

arynes; cyclization; homogeneous catalysis; nickel; three-component reactions; EFFICIENT 1,2-DEHYDROCARBORANE PRECURSOR; POLYCYCLIC AROMATIC-HYDROCARBONS; RING-OPENING REACTION; TERMINAL ALKYNES; NAPHTHALENE DERIVATIVES; COUPLING REACTIONS; BICYCLIC OLEFINS; ENE REACTIONS; ACETYLENES; CARBORYNE;

D O I：

10.1002/anie.200902006

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three in one: Nickel-catalyzed three-component cycloaddition reactions of readily available arynes, activated alkenes, and alkynes gave a series of substituted 1,2-dihydronaphthalenes in moderate to very good yields with excellent chemo- and regioselectivity (see scheme, TMS=trimethylsilyl, cod=1,5-cyclooctadiene). © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5729 / 5732

页数：4

共 62 条

[31]

Liu Z., 2007, ANGEW CHEM-GER EDIT, V119, P2587

[32] Palladium-catalyzed, sequential, three-component cross-coupling of aryl halides, alkynes, and arynes [J].