Localization of the hypothetical protein Cpn0797 in the cytoplasm of Chlamydia pneumoniae-infected host cells

被引：14

作者：

Dong, Feng ^{[1
]}

Flores, Rhonda ^{[1
]}

Chen, Ding ^{[1
]}

Luo, Jianhua ^{[1
]}

Zhong, Youmin ^{[1
]}

Wu, Zhongming ^{[1
]}

Zhong, Guangming ^{[1
]}

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Microbiol & Immunol, San Antonio, TX 78229 USA

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 11期

关键词：

D O I：

10.1128/IAI.00855-06

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Using antibodies raised with chlamydial fusion proteins, we have localized a protein encoded by the hypothetical open reading frame Cpn0797 in the cytoplasm of Chlamydia pneumoniae-infected host cells. The anti-Cpn0797 antibodies specifically recognized Cpn0797 protein without cross-reacting with either CPAFcp or Cpn0796, the only two proteins known to be secreted into the host cell cytosol by C. pneumoniae organisms. Thus, Cpn0797 represents the third C. pneumoniae protein secreted into the host cell cytosol experimentally identified so far.

引用

页码：6479 / 6486

页数：8

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