Surfactant-assisted sol-gel synthesis of forsterite nanoparticles as a novel drug delivery system

被引:44
作者
Hassanzadeh-Tabrizi, S. A. [1 ]
Bigham, Ashkan [2 ]
Rafienia, Mohammad [3 ]
机构
[1] Islamic Azad Univ, Najafabad Branch, Young Researchers & Elite Club, Najafabad, Isfahan, Iran
[2] Islamic Azad Univ, Najafabad Branch, Adv Mat Res Ctr, Dept Mat Engn, Najafabad, Isfahan, Iran
[3] Isfahan Univ Med Sci, Biosensor Res Ctr, Esfahan, Iran
来源
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2016年 / 58卷
关键词
Forsterite; Sol-gel method; Nanoparticles; Surfactant; REVERSE MICROEMULSION SYNTHESIS; LOW-TEMPERATURE SYNTHESIS; NANOCRYSTALLINE FORSTERITE; LUMINESCENCE PROPERTIES; NANOPOWDER; HYDROXYAPATITE; BIOCOMPATIBILITY; OPTIMIZATION; COMPOSITES; RELEASE;
D O I
10.1016/j.msec.2015.09.020
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
082905 [生物质能源与材料]; 100103 [病原生物学];
摘要
In the present study, forsterite nanoparticles were synthesized via surfactant-assisted sol-gel method using cetyltrimethyl ammonium bromide (CTAB) as a surfactant. The effects of CIAB contents and heat treatment on the textural properties and drug release from nanoparticles were investigated. The synthesized powders were studied by X-ray diffraction, Fourier transform infrared spectra, Brunauer-Emmett-Teller surface area analysis and transmission electron microscope images. Mg2SiO4 materials demonstrated mesoporous characteristics and large specific surface area ranging from 159 to 30 m(2)/g. The TEM results showed that forsterite nanorods had diameters about 4 nm and lengths ranging from 10 to 60 nm. It was found that the samples with 6 g CTAB show slower drug release rate than the other specimens, which is due to smaller pore size. This study revealed that the drug delivery of forsterite can be tailored by changing the amount of surfactant. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:737 / 741
页数:5
相关论文
共 40 条
[1]
Development of synthetic CaO sorbents via CTAB-assisted sol-gel method for CO2 capture at high temperature [J].
Akgsornpeak, Akarat ;
Witoon, Thongthai ;
Mungcharoen, Thumrongrut ;
Limtrakul, Jumras .
CHEMICAL ENGINEERING JOURNAL, 2014, 237 :189-198
[2]
Microwave synthesis and sintering of forsterite nanopowder produced by high energy ball milling [J].
Bafrooei, H. Barzegar ;
Ebadzadeh, T. ;
Majidian, H. .
CERAMICS INTERNATIONAL, 2014, 40 (02) :2869-2876
[3]
Modulation of indomethacin release from ZrO2/PCL hybrid multilayers synthesized via sol gel dip coating [J].
Catauro, M. ;
Bollino, F. ;
Papale, F. ;
Pacifico, S. .
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2015, 26 :10-16
[4]
Low temperature synthesis of forsterite from hydromagnesite and fumed silica mixture [J].
Chen, Liugang ;
Ye, Guotian ;
Wang, Qingfeng ;
Blanpain, Bart ;
Malfliet, Annelies ;
Guo, Muxing .
CERAMICS INTERNATIONAL, 2015, 41 (02) :2234-2239
[5]
A new method to produce macropores in calcium phosphate cements [J].
del Real, RP ;
Wolke, JGC ;
Vallet-Regí, M ;
Jansen, JA .
BIOMATERIALS, 2002, 23 (17) :3673-3680
[6]
Microemulsion synthesis and magnetic properties of hydroxyapatite-encapsulated nano CoFe2O4 [J].
Foroughi, Firoozeh ;
Hassanzadeh-Tabrizi, S. A. ;
Amighian, Jamshid .
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2015, 382 :182-187
[7]
Synthesis of an alumina-YAG nanopowder via sol-gel method [J].
Hassanzadeh-Tabrizi, S. A. ;
Taheri-Nassaj, E. ;
Sarpoolaky, H. .
JOURNAL OF ALLOYS AND COMPOUNDS, 2008, 456 (1-2) :282-285
[8]
Hassanzadeh-Tabrizi SA, 2014, J CERAM PROCESS RES, V15, P207
[9]
Polyacrylamide gel synthesis and sintering of Mg2SiO4:Eu3+ nanopowder [J].
Hassanzadeh-Tabrizi, S. A. ;
Taheri-Nassaj, E. .
CERAMICS INTERNATIONAL, 2013, 39 (06) :6313-6317
[10]
Synthesis and luminescence properties of YAG:Ce nanopowder prepared by the Pechini method [J].
Hassanzadeh-Tabrizi, S. A. .
ADVANCED POWDER TECHNOLOGY, 2012, 23 (03) :324-327