Measurement of the different affinities of the two halves of glycopeptide dimers for acetate

被引：9

作者：

Bardsley, B ^{[1
]}

Williams, DH ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT CHEM,CAMBRIDGE CTR MOL RECOGNIT,CAMBRIDGE CB2 1EW,ENGLAND

来源：

CHEMICAL COMMUNICATIONS | 1997年 / 11期

关键词：

D O I：

10.1039/a702128c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The titration of sodium acetate into solutions of the vancomycin group antibiotics eremomycin and chloroeremomycin has been studied by observing the downfield movement of the H-1 NMR signals due to amide protons in the antibiotic binding pocket; this change in chemical shift has been used to determine the different affinities of the two halves of the dimers for acetate ligand.

引用

页码：1049 / 1050

页数：2

共 16 条

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