Functionalized pyridylboronic acids and their Suzuki cross-coupling reactions to yield novel heteroarylpyridines

被引：110

作者：

Parry, PR

Wang, CS

Batsanov, AS

Bryce, MR

Tarbit, B

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

[2] Seal Sands Chem Ltd, Middlesbrough TS2 1UB, Cleveland, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 21期

关键词：

D O I：

10.1021/jo020388b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Bromo-5-pyridylboronic acid 2a, 2-chloro-5-pyridylboronic acid 2b, 2-methoxy-5-pyridylboronic acid 2c, and 5-chloro-2-methoxy-4-pyridylboronic acid 4 have been synthesized and shown to undergo palladium-catalyzed cross-coupling reactions with heteroaryl bromides to yield novel heteroarylpyridine derivatives. The X-ray crystal structures of 2a and 2b have been obtained.

引用

页码：7541 / 7543

页数：3

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