The road much traveled: trafficking in the cell nucleus

被引：80

作者：

Gorski, Stanislaw A. ^{[1
]}

Dundr, Miroslav ^{[1
]}

Misteli, Tom ^{[1
]}

机构：

[1] NCI, NIH, Bethesda, MD 20892 USA

来源：

CURRENT OPINION IN CELL BIOLOGY | 2006年 / 18卷 / 03期

关键词：

D O I：

10.1016/j.ceb.2006.03.002

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.

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收藏

页码：284 / 290

页数：7

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