Bioactivation of selective estrogen receptor modulators (SERMs)

被引：55

作者：

Dowers, Tamara S. ^{[1
]}

Qin, Zhi-Hui ^{[1
]}

Thatcher, Gregory R. J. ^{[1
]}

Bolton, Judy L. ^{[1
]}

机构：

[1] Univ Illinois, Dept Med Chem & Pharmacognosy, Coll Pharm, Chicago, IL 60612 USA

来源：

CHEMICAL RESEARCH IN TOXICOLOGY | 2006年 / 19卷 / 09期

关键词：

D O I：

10.1021/tx060126v

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：1125 / 1137

页数：13

共 146 条

[1] Randomized, double-blind, multicenter trial comparing two doses of arzoxifene (LY353381) in hormone-sensitive advanced or metastatic breast cancer patients [J].

Baselga, J ;

Llombart-Cussac, A ;

Bellet, M ;

Guillem-Porta, V ;

Enas, N ;

Krejcy, K ;

Carrasco, E ;

Kayitalire, L ;

Kuta, M ;

Lluch, A ;

Vodvarka, P ;

Kerbrat, P ;

Namer, M ;

Petruzelka, L .

ANNALS OF ONCOLOGY, 2003, 14 (09) :1383-1390

[2] STEROID-HORMONE RECEPTORS - MANY ACTORS IN SEARCH OF A PLOT [J].

BEATO, M ;

HERRLICH, P ;

SCHUTZ, G .

CELL, 1995, 83 (06) :851-857

[3] Tamoxifen - DNA adduct formation in human endometrium [J].

Beland, FA ;

Marques, MM ;

da Costa, GG ;

Phillips, DH .

CHEMICAL RESEARCH IN TOXICOLOGY, 2005, 18 (10) :1507-1509

[4] Analysis of tamoxifen-DNA adducts in endometrial explants by MS and 32P-postlabeling [J].

Beland, FA ;

Churchwell, MI ;

Hewer, A ;

Phillips, DH ;

da Costa, GG ;

Marques, MM .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 320 (02) :297-302

[5] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF TAMOXIFEN, TOREMIFENE AND THEIR MAJOR HUMAN METABOLITES [J].

BERTHOU, F ;

DREANO, Y .

JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1993, 616 (01) :117-127

[6] THE INFLUENCE OF 4-ALKYL SUBSTITUENTS ON THE FORMATION AND REACTIVITY OF 2-METHOXY-QUINONE METHIDES - EVIDENCE THAT EXTENDED PI-CONJUGATION DRAMATICALLY STABILIZES THE QUINONE METHIDE FORMED FROM EUGENOL [J].

BOLTON, JL ;

COMEAU, E ;

VUKOMANOVIC, V .

CHEMICO-BIOLOGICAL INTERACTIONS, 1995, 95 (03) :279-290

[7] Quinoids, quinoid radicals, and phenoxyl radicals formed from estrogens and antiestrogens [J].

Bolton, JL .

TOXICOLOGY, 2002, 177 (01) :55-65

[8] Role of quinones in toxicology [J].

Bolton, JL ;

Trush, MA ;

Penning, TM ;

Dryhurst, G ;

Monks, TJ .

CHEMICAL RESEARCH IN TOXICOLOGY, 2000, 13 (03) :135-160

[9]

BORGNA JL, 1981, J BIOL CHEM, V256, P859

[10] Correspondence regarding M. Sharma et al., "Antioxidant inhibits tamoxifen-DNA adducts in endometrial explant culture" [J].

Brown, K ;

Carmichael, PL .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2003, 310 (04) :1039-1039

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