Characterization of combinatorial polymer blend composition gradients by FTIR microspectroscopy

被引：46

作者：

Eidelman, N ^{[1
]}

Simon, CG ^{[1
]}

机构：

[1] NIST, Amer Dent Assoc Fdn, Paffenbarer Res Ctr, Gaithersburg, MD 20899 USA

来源：

JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY | 2004年 / 109卷 / 02期

关键词：

biomaterials; combinatorial methods; combinatorial materials science; FTIR microspectroscopy; high-throughput assay; low-e glass; poly(lactic acid); polymer blends;

D O I：

10.6028/jres.109.014

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

A new FTIR technique was developed for characterizing thin polymer films used in combinatorial materials science. Fourier transform infrared microspectroscopy mapping technique was used to determine the composition of polymer blend gradients. Composition gradients were made from poly(L-lactic acid) (PLLA) and poly(D, L-lactic acid) (PDLLA) in the form of thin films (6 cm x 2 cm) deposited on IR reflective substrates. Three composition gradient films were prepared and characterized. The results demonstrate the reproducibility and feasibility of a new, high-throughput approach for preparing and characterizing polymer composition gradients. The combination of composition gradient film technology and automated nondestructive FTIR microspectroscopy makes it possible to rapidly and quantitatively characterize polymer composition gradients for use in combinatorial materials science.

引用

页码：219 / 231

页数：13

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