Rat brain monoamines after acute and chronic myo-inositol treatment

被引：12

作者：

Einat, H

Belmaker, RH

Kopilov, M

Klein, E

Gazawi, H

Ben-Shachar, D

机构：

[1] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva Mental Hlth Ctr, Beer Sheva, Israel

[2] Technion Israel Inst Technol, Rambam Med Ctr, Dept Psychiat, Haifa, Israel

[3] Technion Israel Inst Technol, Fac Med, Haifa, Israel

来源：

EUROPEAN NEUROPSYCHOPHARMACOLOGY | 1999年 / 10卷 / 01期

关键词：

inositol; monoamines; HPLC; depression; anxiety;

D O I：

10.1016/S0924-977X(99)00047-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Inositol was reported to have effects in depression, panic disorder and OCD, and in animal models of depression and anxiety. The present study tested whether inositol treatment alters monoamine systems. Brain areas of rats pre-treated with acute or chronic inositol were analysed by HPLC for monoamines and their metabolites and compared to control animals. Inositol treatment had no significant effect on levels of monoamines, their metabolites, or turnover rates compared to controls. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：27 / 30

页数：4

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