Antioxidant phenolic and quinonemethide triterpenes from Cheiloclinium cognatum

被引:49
作者
Jeller, AH
Silva, DHS
Liao, LM
Bolzani, VDS
Furlan, M
机构
[1] Univ Estadual Paulista, Inst Quim, BR-14801900 Araraquara, SP, Brazil
[2] Univ Estadual Mato Grosso Sul, Dept Quim, BR-79804970 Dourados, MS, Brazil
[3] Univ Fed Goias, Inst Quim, BR-74001970 Goiania, Go, Brazil
基金
巴西圣保罗研究基金会;
关键词
Cheiloclinium cognatum; hippocrateaceae; quinonemethide triterpenes; phenolic triterpene; antioxidant activity;
D O I
10.1016/j.phytochem.2004.03.039
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The triterpenes, 22beta-hydroxypristimerin and cognatine, were isolated together with the known compounds pristimerin, maytenin, 20alpha-hydroxymaytenin, 22beta-hydroxymaytenin, netzahualcoyol, netzahualcoyondiol and netzahualcoyone from root bark of Chei-Ioclinium cognatum. The structures of the isolated compounds were elucidated by interpretation of their spectral data, including gHMQC and gHMBC experiments. The isolates were investigated for their radical scavenging abilities through a spectrophotometric assay involving reduction of 2,2-diphenyl-picryl hydrazyl (DPPH). (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1977 / 1982
页数:6
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