p53 from pathway to therapy

被引：29

作者：

Lane, D ^{[1
]}

机构：

[1] Univ Dundee, Ninewells Hosp, Dept Surg & Mol Oncol, Dundee DD1 9SY, Scotland

来源：

CARCINOGENESIS | 2004年 / 25卷 / 07期

关键词：

D O I：

10.1093/carcin/bgh186

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In the 25 years since its first description the p53 protein has been shown to play a key role in both tumour suppression and aging. New discoveries about the function and control of p53 continue to emerge every month and attempts to exploit the system to develop better therapeutics and diagnostics are beginning to be successful in the clinic (1,2).

引用

页码：1077 / 1081

页数：5

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